Microfluidics Solutions
PDMS Alignment System
Product Overview
The PDMS Layer Alignment System (INFAB-microAlign) is a precision instrument designed for accurate
alignment of PDMS layers and PDMS-to-glass assemblies in microfluidic device fabrication. This
advanced system combines a high-precision 4-axis stage with an integrated microscopy system to
achieve alignment accuracy of ±10 μm, making it essential for multi-layer microfluidic device assembly
and complex channel network fabrication.


Straight Channel Designs
Description: Simple linear or branched channels.
Application:
Basic fluid transport and calibration.
Used as reference structures or for testing flow resistance.
Can also serve as connectors for multi-chip integration.
Serpentine / Mixing Structures
Description: The zig-zag / serpentine design on the wafer.
Application:
Enhances mixing of two or more fluids through chaotic advection.
Common in biochemical assays, drug mixing, and reagent preparation.
Droplet Generator Designs (T-junction / Flow-focusing)
Description: Junctions where one channel intersects another at 90° or narrow gaps.
Application:
Single and double emulsion droplet generation.
Used for encapsulating cells, beads, or reagents.
Typical in drug delivery, organ-on-chip, and diagnostics.
Cell Trapping / Chamber Designs
Description: Rectangular or box-like chambers with inlet/outlet ports.
Application:
Cell culture chambers for organ-on-chip systems.
Can be used for trapping cells, spheroids, or particles.
Applications in cancer-on-chip, toxicity testing, and tissue modeling.
Constriction / Resistance Channels
Description: Narrow sections between wider channels.
Application:
Flow resistance measurement.
Shear stress experiments.
Can be used for deformability studies (RBC, CTC analysis).
